Welcome, I have been here for almost a week now, and no one welcomed me! I think I have a hunch.
Anyway, if you play very compressed music very loudlit may cause a problem, but my guess is your amp is either failing or clipping.
Clipping happens when you overdrive your amp. Its much easier to damage a speaker with an underpowered amp than by using an amp that can deliver more power than your speakers are rated to handle. A simple way to explain headroom is extra power so that when the program contains bursts of loud sound the amp can deliver clean power without overloading. "Clipping" refers to distortion that looks on a scope like the top of the waveform is "clipped" off. It's usually more likely to fry a tweeter, but can damage woofers too.
Check your speaker connections first. If the speaker has biwire connection, make sure the jumpers are making contact. Next step is to switch speaker wires to see if a channel of your amp is out. You might want to use more caution and use a different amp to test the speakers in case your amp has become a speaker killer.
good luck!