If you are fortunate enough to own a pair of Klipsch horn loaded speakers, you should seriously consider finding or building a tube amp. Many music lovers consider Dynaco and Klipsch to be the path to musical nirvana. Kevin from Dynakitparts.com tells me the Dynakit Stereo 35 paired with some highly efficient horn speakers is some of the best sound he's ever heard. The Klipsch forums are another good source of info about Dynaco amps.
The original Dynaco designs are among the best tube amps ever made. You can buy better tube amps, but you had better be prepared to spend a whole lot of money. If you absolutely must have the best of the best and you can afford it, then look for some Conrad-Johnson tube hifi gear.
http://santafemusic.blogspot.com/2008/09/tube-be-or-not-tube-be.html