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Bosco-d-gama

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Posts posted by Bosco-d-gama

  1. 3 hours ago, RandyH000 said:

    this is an online amateur article -let's see who is behind the latest Colchicine research -

     

    COLCORONA was coordinated by the Montreal Heart Institute’s Montreal Health Innovations Coordinating Center (MHICC), and funded by the Government of Quebec, the National Heart, Lung, and Blood Institute of the U.S. National Institutes of Health (NIH), Montreal philanthropist Sophie Desmarais, and the COVID-19 Therapeutics Accelerator, an initiative launched by the Bill & Melinda Gates Foundation, Wellcome and Mastercard. CGI, Dacima and Pharmascience of Montreal were also collaborators in the trial.

    https://www.globenewswire.com/news-release/2021/01/23/2163112/0/en/Colchicine-reduces-the-risk-of-COVID-19-related-complications.html

     

     

    Kudos to the systems intent on confirming the application, or disproving the application. We all witnessed the follies of wishful hoping when it comes to real medicine. Colchicine is nasty stuff and must be administered properly. Looking forward to hearing more about this and other promising approaches. As poorly as the vaccinations are going it could well be that new definitive treatments will eclipse their purpose. If we find that we can easily cure or treat covid19 there’s less need to attempt to prevent infections. 

  2. 49 minutes ago, BigStewMan said:

    I often take a walking tour of my old haunts and see what's the same and what has changed. it's fun. My brother just told me last night that he was looking at our childhood home on Google Earth and never realized how big the backyard was. 

    unrelated; but still interesting ... my parents both died within five months of each other ... I was eight years old. Obviously, California wouldn't let me live there alone so I got shipped off to live with relatives ... then later different relatives. Anyway, years later my cousin is now married and her husband's co-worker is having a party and they're invited. she is walking up to the door and stops and says "I can't go in there."  her husband asks why and she says "this is house that aunt & uncle lived in."  she went in, but said she was really freaked out. 

    I do the same thing. The family lived in West Los Angeles in several different neighborhoods. Because of the ginormous property values there all but one of my childhood homes have been dramatically remodeled. That one house is in Venice and it is the only one that tugs on the heartstrings. The rest are all very nice but do not engage my nostalgia. Maybe it’s time for more therapy?

  3. 11 hours ago, RandyH000 said:

    Quebec researchers say they have found an effective drug to fight COVID-19

    Dr. Jean-Claude Tardif, who led the study, this is a "major scientific discovery," he said. Colchicine is the first "effective oral drug to treat out-of-hospital patients."

     

    The ColCorona study involved 4,159 patients whose diagnosis of COVID-19 had been confirmed by a nasopharyngeal test (PCR).

    https://montreal.ctvnews.ca/quebec-researchers-say-they-have-found-an-effective-drug-to-fight-covid-19-1.5279310

     

    Proceed cautiously. Everyone wants to find some optimism in fighting covid19 but it had better be a LOT more than smoke and mirrors before you go proclaiming success. So far none of the singular drugs have met the magic bullet definition. Don’t get me wrong. I am extremely pleased to see the efforts undertaken to find the real cure. But leave the klaxon alone until you are certain it merits ‘klaxon’ level enthusiasm.

     

    https://www.statnews.com/2021/01/23/colchicine-gout-drug-shows-promise-for-covid-19/

  4. 6 minutes ago, Zim. said:

    learn how to season your food and you won't have a need for hot sauce...

    Respectfully disagree. There are many seasonings and combinations thereof. ‘Hot sauce’ per se umbrellas thousands of options and some most wonderful ones at that. My favorite is a chili meat loaf sandwich well laden with mayonnaise and ye olde Tabasco. 

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  5. 15 minutes ago, RandyH000 said:

    CDC forecasts up to 100,000 more Covid-19 deaths in the next few weeks

    The United States could face as many as 100,000 more Covid-19 deaths in less than a month, according to the US Centers for Disease Control and Prevention.

    https://www.cnn.com/2021/01/21/health/us-coronavirus-thursday/index.html

    “Without modern medicine and hygiene covid19 deaths could/would have been comparable or worse to the 1918/19 influenza.” 
     

    https://www.cnbc.com/2020/08/13/scientists-say-the-coronavirus-is-at-least-as-deadly-as-the-1918-flu-pandemic.html

  6. 59 minutes ago, RandyH000 said:

    are  you saying that  fever blisters and Covid are related

    They are both viral pathogens but they are not morphologically related. Covid19 and some forms of common cold viruses are morphologically related. They are all types of Corona viruses. Some are just more virulent than others.

  7. 20 minutes ago, RandyH000 said:

    Not sure if this is  related -

    Researchers Investigate Coinfection of COVID-19, Herpes Zoster

     

    https://www.pharmacytimes.com/news/researchers-investigate-coinfection-of-covid-19-herpes-zoster

    Roughly related. Essentially it reports that a covid19 infections has resulted other viruses becoming expressed at the same time causing coinfections. Secondary infections are part and parcel in a lot of medical care for a variety of reasons.

  8. 16 minutes ago, CECAA850 said:

    I was talking to a vendor that services our store yesterday who has had it recently.  He had the typical loss of smell and taste but for him the worst part was lower intestinal.  He said it was like food poisoning.  I didn't realize that was a symptom.

     

    On a side note, we had our first co-worker get tested yesterday.  We should know hopefully by tomorrow what his result of the PCR test was.  The Dr's office said that he had swollen glands and several other indicators of covid.  Oddly enough, his symptoms started out with his lower intestine also.

    Yes covid19 is known to cause some ugly gastrointestinal situations. There’s a constellation of symptoms for covid19 some of which are directly related to the virus and others caused by bodies immune responses to the viral infection.
     

    When’s the last time you suffered from a fever blister? Usually these things show up when we’re stressed and for some reason tend to express themselves on our lips. They’re very painful and they spread. They are viral infections caused by a type of herpes simplex virus. The herpes virus lives in us (90% carry it) and our bodies usually keep it tamped down but stress allows it to develop these acute local flare ups. But that awful blister is how viral infections work. The virus uses our own cells to replicate - then those infected cells die and basically explode strewing more virus to invade other cells to do the same thing. Notice how a fever blister often spreads to adjacent tissues? The virus invades, replicates, kills the host cell and its prodigy moves on to infect other cells and repeats the cycle.

     

    Well our bodies know the herpes virus and will end the flare up and the herpes will once again go dormant. This is not the case with new pathogenic viruses. They just run amok in the body until the immune system learns how to respond. So imagine fever blisters in your lungs or pancreas or your gut. All pathogens are nasty. If they were mammals they’d be hyena packs. If it was 100 years ago people would take the covid19 pandemic much more seriously simply because then they would’ve known death from infectious disease. They’d have respect for avoiding the infection and not question it’s virulence let alone it’s existence. Way more Americans died from the 1918/19 flu than were killed in WW1.

    .

    Sorry for the lengthy reply and it was not aimed at anyone specific. I just get all informative at times, especially after going to the store and seeing the dunderheads sans masks 😷😠.

  9. 38 minutes ago, wuzzzer said:

    Thanks everyone.  It's the kind of thing that makes me feel better when I talk to others about it.  I just wish the weather was nicer so I could spend more time outside.  It's supposed to be almost 40 tomorrow so I'm saving the shoveling of the snow we got today until tomorrow.  🙂

    Jeez you got that right. Between the short daylight and cloudy days I truly abhor this time of year. Fortunately we’ve had just a few snowfalls of merit and they’ve cleared up. In fact weather wise we’ve had more rain than snow than I can recall. But boy the sunny days just light up your soul. We try to get out and walk twice a day regardless. That’s a wee challenge for me since I had both hips replaced in the last 3 months. But one must plow forward........😎

    • Like 1
  10. 27 minutes ago, RandyH000 said:

    Covid 19 is putting all countries around the world in financial dire strait ,  where have you been ?

    Agreed......    and IMHO China needs to be held economically accountable to some degree for these circumstances. There’s no question that China dragged its feet when covid19 initially plagued their country. China knows better. They demonstrated extremely poor judgement in seeding disinformation and misinformation about covid19 early on. This was the best opportunity to stifle the disease and it was squandered for no good or rational reason. The should be consequences so the next time this occurs the proper responses are put in play immediately.

  11. 44 minutes ago, tube fanatic said:


    The CDC says that 94% of those who have died with the virus had underlying medical issues. So how can you imply that none of 400,000 would have died had they not been infected with the virus?  What is the basis of your presumed conclusion that all would still be alive if the virus didn’t exist?   I have been told that if a person tested positive within 30 days of dying in an auto accident, as one example, the cause of death is attributed to the virus.  This does not mitigate the seriousness of the situation.  Rather, I believe the media are using a strategy of creating fear and panic.

     

    Maynard

    Death statistics are just a single dimension to covid19. Granted they are the most egregious and sensational and immediate but dying right away seems to be the only number that impacts most people. So FWIW we do have this many Americans with covid19 in their death certificates. Related to this number is what’s called ‘excess deaths’. Excess deaths compares the average annual death rates seen in the past with the death rates seen with covid19. As of October 2020 there were 300,000 excess deaths compared to prior years. So the answer to your inquiry is ‘yes’ there are a lot more Americans dying because of covid19 than in prior years. In fact the average age of those dying and shear number of the dead has reduced the averaged life span for Americans by 1 year. All of these values support the seriousness of the immediate lethality of covid19.

     

    Now as to the long term consequences of covid19 infections this remains to be seen. But we do know that covid19 leaves lasting scars on several organ systems. In every regard any process that scars a healthy body causes that body to accelerate its decline in health with age. The sequelae of covid19 infections could be astronomical. In 10 to 20 years the millions of covid19 survivors could be facing a host of chronic health problems any of which could accelerate their demise and all will have some consequences whether economic or in quality of life issues.

     

    Covid19 is no joke and the sooner we can contain it the better. The longer is remains active to more likely it will mutate into something more menacing.

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  12. Here’s an article covering the inception of covid19 in the USA. 1 year ago we had case #1. 1 year later and we have 400,000 dead. I’ll say this again. In WW2 we lost 422,000 soldiers in the entire war. This is death on a wholesale scale. Things are looking better but it is not time for any victory lap. It is time to double down, keep covid19 on the ropes and make it a manageable disease.

     

    https://www.usatoday.com/in-depth/news/nation/2021/01/19/first-covid-case-us-year-anniversary-snohomish-county/4154942001/

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  13. Here’s an overview article on how the covid19 mutations are occurring. For now they feel that these mutant strains remain manageable but certainly can change. It is surmised that covid19 mutations occur more often in immune compromised victims. When a normal person gets covid19 their immune system ‘goes to town’ on the virus and the ailment ends in a typical time frame. But immune compromised covid19 turn into ‘long termers’ and the virus genetically percolates seeking ways to survive/thrive inside the human body. This is when covid19 evolves new survival modifications aimed at defeating the human immune system. They may not be more virulent/lethal but these new variants infect human cells more easily. So fewer covid19 viruses could result in more serious cases where before they’d not present as acutely. Science is studying these mutations closely. They’re finding the same type of mutations evolving independently so the new English variant is similar to another variant from elsewhere. The paper is an interesting and informative read.

     

    https://www.theatlantic.com/health/archive/2021/01/coronavirus-evolving-same-mutations-around-world/617721/

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  14. 31 minutes ago, dwilawyer said:

    Anything on Moderna in this regard? My mom had it 2 weeks ago, 82, my Dad just had a rotor-rooter done, he is 89 and wants it, but his cardiologist wants him to wait a couple of weeks.

    I know nothing other than what’s available online. If you look at the statistics here the risk, though greater, remains small. I suggest you rely on your care providers. 

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  15. 1 hour ago, Shiva said:

    Here, let me help. Norway is reporting that people over 80 given the vaccine are realizing higher incidences of complications including fatalities. Vaccine manufacturers report that their safety tests did not include people over the age of 75. This increase in complications is notable but not extreme IMHO. 

  16. 8 minutes ago, Coytee said:

    Maybe Dracula was really on to something

    Nah........   Draculas’ intake was more like eating blood sausage only ‘fresher’. A partial exchange transfusion is more like changing the oil in your vehicle. Out with the bad - in with the good.

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