MicroMara
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Posts posted by MicroMara
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@JohnJ Robert Plant is magnificent..great Song ( Got my eyes on you ) and sound quality
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1 minute ago, Full Range said:
Apart from the LPs and CDs I have of Frank Zappa
I also have this book
I adore him in the same way ......
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Infizierte = infected / Todesfälle = death / Genesen = recovered / Weltweit = World wide
The number of recoveries is constantly increasing, but is not yet in proportion to the number of new infections. But shows a trend reversal
Lübeck - Researchers Linlin Zhang and Rolf Hilgenfeld from the University of Lübeck have achieved a real breakthrough. They were able to decipher an enzyme that is crucial for the proliferation of the novel coronavirus. The researchers also found an inhalable inhibitor that acts against the newly decoded main protease of the SARS-CoV-2 virus.
This specifically concerns the viral main protease Mpro, without which the coronavirus cannot copy its genetic material (RNA) from the host cell and thus reproduce. Closer investigation of the enzyme structure might now help in combating the virus. An inhibitor developed against related coronaviruses has already been effectively tested in mice and cell cultures.
Coronavirus: Research is in full swing - first successes with old inhibitorThe main protease is the decisive factor in fighting the virus, as it cannot reproduce without it. The discovery of the two researchers from Lübeck, Zhang and Hilgenfeld, therefore opens up a new approach for antiviral agents against the novel coronavirus.
The worryingly continuously increasing case numbers* of Covid-19 are putting pressure on researchers worldwide. A suitable vaccine is currently being searched for at breakneck speed - but also for antiviral agents that could contain and thus halt the spread of the pathogen in the body.
Possible successes already seem to be emerging. An inhibitor that was developed by Hilgenfeld and his team a few years ago against the pathogen MERS-CoV and other related corona viruses is also believed to have proved effective against SARS-CoV-2. In the mice, the inhibitor accumulated in the lungs and kidneys as hoped for - these organs are the organs most affected by Covid-19.
Coronavirus: Tests with lung cultures successful - Too late for current pandemic?
But the experiments with human lung cell cultures also worked. In already infected lung cells, the new inhibitor blocked the proliferation of the virus, thus preventing the infection from progressing. According to the researchers, the inhalable inhibitor of the main protease opens up an approach for new drugs against the rampant coronavirus. In addition, the researchers found that the inhibitors were most likely not toxic.
However, the developments will probably come too late to counteract the current pandemic. "It will certainly take several years before our active ingredient is developed into an anti-coronavirus drug," Hilgenfeld said.
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a band called o " a smile is diamond ........
1976 Liberty Records
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SAGA .." Silent Night " Polydor Label 1980 ....
Don´t be late shapter 2
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That was the best time ever...Fischer Z with " Red skies over Paradise " Liberty Records 1981
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It was a great time ......she never comes back
Moon Martin " Bad News " Capitol Records 1980
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Appropriately from the band " Get the Knack " My Sharona " Label - Capitol - 1979 . It was a great time
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19 minutes ago, JohnJ said:She's got a Benetar / Quatro thing going on there... but I know that tune.....
@JohnJ Great Original of Rock´n Roll Gipsy ..........
Heart .....Barracuda 1977
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@Full Range loving Nirvana ..........
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NEW TRIUMVIRAT presents " POMPEIJ" 1977 , Electrola Harvest Label , Musicians ..Dieter Petereit, Barry Palmer, Jürgen Fritz, Curt Cress
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@mustang_flht Well then, we have a lot to talk about until death do us part ....And I would like to welcome you to our ever-growing circle of old rockers
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@dirtmudd Your knowledge around Frank Zappa is very impressive. I take off my hat.
But also all around Genesis......Invisible Touch ....At the climax of their career....Had seen the live concert for this album, a life experience for the human senses
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1 hour ago, Dave1290 said:
I'm STILL laffin my butt off with this gem!
😂
This is really great cinema my friend, I have had a great time...........
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I had to log in again, it does not really belong here, but I find it so interesting that I put the video here...The brand new song by Bob Dylan " Murder most foul "
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1 minute ago, billybob said:
Think it is Munch but no, just a fancier of art. My taste there sometime border upon the
bizzare. Thanks for your posts!
Very much, I just found out myself that the Edvard Munch was missing the "N". It was not intentional. Can happen in the fast of communication.
for now ....1.28 a.m. sunday morning ....
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8 minutes ago, billybob said:
Why thank you. There are many here like that. Anyone that's been here knows I am not all that.
You are fast yourself. I tend to go in spurts.
There is a old short story you brought to mind. The man of the crowd.
Cheers!
Yes, but the man in the crowd is a very special appearance and has a special charisma. But it is certainly not because of your Avatar of Edvard Much " The Scream ". If you own the original painting I have no more questions anyway
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@billybob I have been wondering for a long time how you manage to be in this fantastic forum always and everywhere ? What is your secret ? Your multitasking ability is admirable, how many computers do you use at the same time ?
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9 minutes ago, Dave1290 said:
I don't know how to live without you.
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In the vinyl record spinning already mentioned, the book of Sting, but there is a rare live recording of Sting. Sting Acoustic Live in New Castle
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I don't know if any of you know Jean Luc Ponty... He plays an electric violin.
I heard his live album from 1979. The track " Mirage " might be familiar to some of you...
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19 hours ago, Mossy bottom said:
It's 45 rpm Friday Night...Playing 45 rpm lp's!!!
Started the night out with this Phenomenal reissue.
Dire Straits - Communique.
Yout TT ....Brilliant
....Looks similar to the german´s famous Factory TRANSROTOR.......... Dire Straits .....got the whole collection ....
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20 hours ago, Tigerman said:
Well, I must confess Paul and friends. I decided to go into a COMPLETELY different direction and have totally moved on to a brand new high end audio system. After a lovely 12 years with my beloved Klipschorns and Dynaco tube gear, I have purchased a grand pair of Martin Logan ESL Classics in special order GLOSS black. The amp is a Parasound HALO 21 and the preamp is a matching Halo with Sabre DACs. It will decode the highest DSD and PCM resolution available. With the dynamic range of these unusual speakers couple to a 400 per ch. at 4 ohm amp, they produce a wall of sound that I never thought would rival the Klipschorns !
Thanks to one of the LAST brick and mortar audio stores in my area, I actually was able to listen to this system in a private showroom and fell in love. Here is the very first picture I have posted publicly on a Klipsch forum. Enjoy!
Nice Gear Tigerman , congrats to the Akai Tapemaschine, the Martin Logan Electrostatics, Rega TT and the other , can´t identify right now, equipment. Think it sound brilliant..
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20 hours ago, Tigerman said:
.....the rear cover artwork....
Their best Record....got them all....Prezel Logic, Can´t buy a thrill, AJA ....
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1976 Liberty Records
She's got a Benetar / Quatro thing going on there... but I know that tune.....
Heart .....Barracuda 1977
for now ....1.28 a.m. sunday morning ....
....Looks similar to the german´s famous Factory TRANSROTOR.......... Dire Straits .....got the whole collection ....
The Other Discs
in Lounge
Posted
@JohnJ.... the bass there has been resonating the back of this house in the last hour.