Bosco-d-gama

Been there, done with that. Perhaps it is mantra but some folks seem to have ‘bad’ tube luck. Anyway I went with high end solid state. I use an Accuphase E530 integrated amp. Never looked back. The unit has required 1 service in 12 years of pretty much daily usage.

Y’know they can cut through the red tape if they wanna. Anaphylaxis occurs at 2 cases per million. Keep an ambulance on stand by like most HS football games.

Effective population vaccinations for the influenza are considered anything above a 60% success rate. A population with this level of immunity will impede the spread of the flu enough to quell an outbreak. I believe I have read where they want something similar or better for covid19. The vaccines themselves achieve individual functional levels above 90% which is extraordinary. But to impede new variations we need to get as many vaccinated ASAP and adhere to masking, etc for the balance of this calendar year, if not longer. Insofar as logistics go..... not my bailiwick. What I would note is that large sized installations are needed to accommodate large crowds. A queue at the local pharmacy isn’t gonna work. Hopefully brighter minds than mine are working on the solutions.

Every retired nurse, medic, doctor, Pharmd and anyone willing to undergo 30 minutes of training can give a safe IM injection. It truly is abc123 easy...... then again so is wearing a mask.

You do not need MD’s and/or RN’s to administer simple intramuscular injections. It is the same deal as boot camp. Line em up and medics inject - done.

This might be a wrong idea...... but I’d like to see the national guard deployed to administer these vaccinations. I think they need a simplified command route to distribute and deploy this stuff. With the guard it goes from source to dispensary to the people. Giving IM injections is simple. Now we’ve got too many outlets, too many routes, too many promises and too many chiefs and things are getting bottlenecked, botched, lost and wasted. Simplify it - use the guard IMHO.

You have a PM.....👍

I am hopeful. I wish I was more optimistic. Covid19 is a most challenging foe. Where we’ve lost the biggest battles have been with masses. Fingers and toes crossed.

Edited by Moderator: Absolutely! The need to 911 vaccinate huge masses of people is an enormous task that was [Edit "was" refers to the past, not what thread is about. Here and now.] Who is failing? [Not on topic, you could try new thread, but good luck keeping politics out of that.] Never expect your elected leadership to [that could actually probably be saved, and would be an excellent topic - it would be a discussion on how to handle the next one]

Had a friend whose great aunt was an editor in NYC during the 1st half of the 20th century. She’d inherited a garage full of books. The only one of note I can recall was a Hitler signed copy of Mein Kampf. Guess it was more notorious than note worthy.

Genuinely....... Every window has at least 1 piece hanging (that includes all the bathroom windows) and we have stuff displayed on easels. We have another 25 big pieces stored and about 200 smalls in boxes. We’d planned on the art festivals last year but they got covid19 cancelled. 😔

We all collect memories. Some choose to gather and curate objects of rarity or interest. Some suffered deprived childhoods and just hoard to ‘have’ to nurture that void. For myself the things I keep around my house need to contribute to the whole and that means a mixture more than a collection. One intriguing antique or a piece of art can anchor a wall or niche. But I do not like clutter so there’s no ‘massing’ of collections for the sake of having every element of any genre. My stained glass hobby drives an obscure notion that maybe, someday my work will be desired enough to be considered noteworthy, or collectible. For now each piece is just a challenge. But between the Mrs and myself we have a lot of stained glass. So it constitutes a collection. 👍🤪

Ruh - Roh............. Looks like Cuomo could be in for a code brown, a well deserved code brown.😔 https://www.foxnews.com/politics/new-york-nursing-home-report-reveals-massive-corruption-coverup-scandal

Well it is a stretch. The covid19 vaccines have passed all known testing metrics for safety. Keep in mind that passing is not a perfect score. But the same measures were applied to these vaccines that have been applied to all other vaccines. So in this measure they are essentially the same. What is different is how the covid19 vaccines were derived. This is where the ‘express lane’ was taken that is new. And what’s ‘new’ is not the end goal but the route taken. So to make the Ebola vaccine they knew what they needed and took the traditional long route albeit as fast as they could. We could’ve done the same for covid19 and we’d have the same results in another 12 to 18 months and nowhere near enough vaccine to make much difference at that juncture. Basically they used a man made biological catalyst to speed up the processes to get to the same place they’d have gone otherwise. So it is not as dire as perhaps it sounds and it is working and it is more efficacious than any influenza vaccine ever produced. I’d suggest that we should swell up with pride at the accomplishment and relish what the effort may bring us in the very near future in the form of other drugs.

She might be sitting on something......😏

Here’s another Avenue of medical research aimed at treating infectious diseases. Cutting edge microbiology is poised to make great strides...... if we don’t kill ourselves 1st. https://phys.org/news/2021-01-newly-molecule-disrupts-virus-infections.html

Where we differ is does the cure kill the patient and for the time being it doesn’t. We have covid19 and already it has mutated and it will continue to do so unless we can hamper its spread and recurrence. With what we have we know that a surge of covid19 can bring huge cities and the best medicine can offer to their knees. It has got to end ASAP before it mutates into something uglier. So science has new tools and these tools allow us to accelerate the development of medicines used to treat covid19 and other diseases. As always the proof is in the applications. They’ve done the safety testing and we deployed vaccinations safely. So in a sense covid19 has put humanity in the position of being the guinea pig. We will differ on this need. I believe it is working safely and I believe that the experience will usher in new generations of medicines with unheard potential. It is possible that we will be able to vaccinate against types of cancers (other than HPV). We are moving forward and as it often happens humanity does this when survival challenged. Covid19 brought us to this threshold and new we get to cross into uncharted territories sooner than otherwise.

ADE is different than antibiotic resistant organisms. It is a more subtle relationship of a virus to its host and the host response to a viral infection. Essentially the concern is that a vaccine may inadvertently supercharge the virus. The underlying concern is how these covid19 vaccines have been developed using manufactured DNA methods. Getting the vaccine was quicker because science could build the genetics needed to derive them. But genetics is powerful juju and has its incumbent concerns. Personally I look at it this way. On a separate issue we have global warming. It is clearly related to human activity and it is coming quickly, quicker than it has ever occurred naturally. For some the solution is slam on the carbon emission brakes and duck and cover. For others they seek answers in newly applied carbon capture engineering........ and IMHO this is the only workable answer. That’s because it offers the only solutions that can work enough in the short time frames needed and it is independent of worldwide participation in carbon reduction. Covid medicines are in the same time sensitive situation and advanced science offers the best opportunity to contain them fast enough.

Paraphrasing from the blog post: As yet there’s no definitive proof that antibody dependent enhancement ADE is occurring with covid19. And similarly there’s no demonstration of ADE being part of any vaccine pathways (again per the author). So while his concerns are actual they are not factual. What is clear from this post is just how complex virology is and why people need to listen to the advice from the medical community. As far as ADE goes it is among many pathways that make microorganisms pathological or more pathological, if you will. Looking for the ADE pathway in covid19 is being done and as the author noted it has not been found. If he chooses to fret himself into an ulcer over its prospect he may as well take anxiolytics for earthquakes, tsunamis and asteroids. For now he is merely borrowing trouble when the world has plenty of real covid19 troubles in play.

So - The WHO held a pandemic review conference to study what went wrong with covid19 and their findings are little more than a politically correct solicitation for more funds. For starts they cite lack of preparedness and slow responses with poor communications. They want more $$$ because they feel that they should be the worlds infectious disease watchdog and healthcare facilitator. Technically they are correct. They merely cited the idyllic organizational circumstances that would (have) done much better. But in reality The WHO is nowhere near that idyllic organization and this report emphasizes this point. The key things missing are the very ones that caused the pandemic. The country of origin intentionally withheld timely response and still impedes investigation into covid19 origins. The country of origin is an economic giant and yet offers The WHO 0.02% of their existing budget. I use the term ‘country of origin’ because in this report The WHO never once mentions China. That says that The WHO still bows to state politics and will not ever be the idyllic organization needed to manage/circumvent a pandemic. They are gutless and allow themselves to get used/abused. Covid19 is their billboard of failure and to this day China is defining how the WHO works. But they want more $$$. And guess who will most likely respond and who won’t? They seek to expand their foundations when current events prove these purposes to be unreachable. The WHO needs revamping and absolutely new leadership. The report is a pie-in-the-sky answer. But the real question is why did The WHO fail in their existing mission and they did not examine their own failings....... and today in Wuhan China The WHO continues to fail the world they supposedly serve. https://www.npr.org/sections/goatsandsoda/2021/01/25/959692787/everything-broke-global-health-leaders-on-what-went-wrong-in-the-pandemic

I have hearing aids where the receiver sits up and behind the ear. I am told the microphones are located posterior laterally. In fact functionally they seem to be posterior - pointing backwards. So the sounds they pick up and amplify are from the rear fields. Works okay for just one thing, one on one conversation. More than a few people talking and I pick up more collateral noise than what I am trying to listen to. Music is affected in the same manner. The proverbial ‘sound stage’ is not achievable any longer. Getting elderly sucks big-time. Gotta think that with modern technology that they could do better. This is probably true - but at what cost?

Exacerbation of hearing loss in the elderly, yet another collateral consequence of the covid19 ‘mess’. For those (myself included) with significant hearing deficits being amongst others with everyone in masks has impacted the sense of hearing. Oddly this article does not mention the one thing I’d imagine would be part of the problem - that masks muffle sounds. Anything that confounds transmission of sounds impairs me greatly. Listening in crowds and I simply cannot distinguish individual voices or participate in conversations. I appear disinterested or worse but in fact I simply cannot hear regardless of hearing aids. Now since the covid19 also keeps me away from crowds that is not an issue for now. But imagine being in a long term care facility where everyone wears masks and most residents suffer from hearing dysfunction. The masks must bury the spoken voice for them. https://www.foxnews.com/health/coronavirus-face-masks-hearing-loss-survey

I use Eliptracs but mine are 2 inch. Keeping mine but maybe if you could use the larger driver you might find your horns quicker. I use the older JBL 2482 drivers. Jammin’ Jersey in Southern California should have these drivers and other options. Last I looked there they had a pair of JBL 2480 drivers that are pretty rare. Bruce Edgar said the JBL 2480’s were ideal for Khorn midrange purposes. I could not find any when I was in the building mode.

......gonna run the exhaust full open?

To be more specific. A treatment would be something simply administered that would mitigate the progression of the disease. You’d get sick but nowhere near as seriously ill as we see now. It is like finding the Achilles heel for the pathogen. We do this with tuberculosis now. We could vaccinate for tuberculosis and it would work. It would cost a lot and (in this instance) it will mask skin testing for the disease. So instead of vaccinating for tuberculosis we diagnose active cases and treat the disease. For now we can cure tuberculosis. If we did the same for covid19 then you have a ‘bingo’ moment.