Termites, drainage, moisture in crawlspace, radon, lead based paint, rodents, air leakage, flashing, loose shingles, stains on ceilings, condition of hvac, volatile organic compounds, underground storage tanks, electrical service problems including smoke detection, properly vented gas appliances, rotted wood (especially window/door sills) cracks over door headers, level floors, uneven settleing. Make sure the floors are well supported if you plan to use a turntable[:^)] You are going to have a music room....right?
Tell us about the house such as siding, roof materials, age of systems, one story or two, insulation.......