Bosco-d-gama Posted January 27, 2021 Share Posted January 27, 2021 32 minutes ago, tube fanatic said: Yes, but did you review the links to the FDA, et al, presented by some commenters? As reported in this article, there is concern in Japan (and other countries) about this phenomenon: As reported in Japan Times: https://www.japantimes.co.jp/news/2020/11/25/national/science-health/japan-experts-coronavirus-vaccines-safety/ ‘Dr. Tetsuo Nakayama, a project professor at Kitasato Institute for Life Sciences and director of the Japanese Society of Clinical Virology, says although the vaccines under development by Pfizer and Moderna successfully created antibodies in trials, there are still doubts about whether those antibodies remain a year or two after vaccination. There are also underlying concerns about the vaccines’ safety over the long term. Judging from past precedents, their safety and effectiveness are not something that can be determined until at least a year after a massive number of vaccinations have been administered, experts say. In a worst-case scenario, antibodies could worsen the disease by essentially helping the infection of cells — a phenomenon called antibody dependent enhancement (ADE) — rather than fighting the virus pathogens. For example, a dengue fever vaccine made by Sanofi, based on a yellow fever vaccine embedded with a part of the dengue virus genome, at first appeared to be effective. But it caused the deaths of children who had been given the vaccination due to the ADE phenomenon. “Concerns over ADE still remain. I am an elderly person myself, but if I were asked, I would say I don’t want to get a shot,” Nakayama said. “Not all of the 120 million people (in Japan) should get the vaccinations. Children, for example, would not need it because there’s scarcely any risk of severe cases.” ‘ I guess where we differ is that I consider information from FDA and CDC as being the least truthful in comparison with what is disclosed by similar agencies in the rest of the world. It seems that the domestic point of view is different more often than in agreement. To each his own..... Maynard Where we differ is does the cure kill the patient and for the time being it doesn’t. We have covid19 and already it has mutated and it will continue to do so unless we can hamper its spread and recurrence. With what we have we know that a surge of covid19 can bring huge cities and the best medicine can offer to their knees. It has got to end ASAP before it mutates into something uglier. So science has new tools and these tools allow us to accelerate the development of medicines used to treat covid19 and other diseases. As always the proof is in the applications. They’ve done the safety testing and we deployed vaccinations safely. So in a sense covid19 has put humanity in the position of being the guinea pig. We will differ on this need. I believe it is working safely and I believe that the experience will usher in new generations of medicines with unheard potential. It is possible that we will be able to vaccinate against types of cancers (other than HPV). We are moving forward and as it often happens humanity does this when survival challenged. Covid19 brought us to this threshold and new we get to cross into uncharted territories sooner than otherwise. 1 1 Link to comment Share on other sites More sharing options...
Bosco-d-gama Posted January 27, 2021 Share Posted January 27, 2021 Here’s another Avenue of medical research aimed at treating infectious diseases. Cutting edge microbiology is poised to make great strides...... if we don’t kill ourselves 1st. https://phys.org/news/2021-01-newly-molecule-disrupts-virus-infections.html 1 Link to comment Share on other sites More sharing options...
billybob Posted January 27, 2021 Share Posted January 27, 2021 Sanofi to help with vaccine: https://www.bloomberg.com/news/articles/2021-01-27/sanofi-to-make-millions-of-biontech-pfizer-s-covid-vaccine-doses 1 Link to comment Share on other sites More sharing options...
CECAA850 Posted January 27, 2021 Author Share Posted January 27, 2021 3 hours ago, Bosco-d-gama said: So in a sense covid19 has put humanity in the position of being the guinea pig. We will differ on this need. I believe it is working safely and I believe that the experience will usher in new generations of medicines with unheard potential. Covid19 brought us to this threshold and new we get to cross into uncharted territories sooner than otherwise. That's a great way to look at it. Most people prefer not to be Guinea pigs and that's exactly how it feels. Uncharted territories with no long term studies make me uneasy as well. 1 Link to comment Share on other sites More sharing options...
Bosco-d-gama Posted January 27, 2021 Share Posted January 27, 2021 27 minutes ago, CECAA850 said: That's a great way to look at it. Most people prefer not to be Guinea pigs and that's exactly how it feels. Uncharted territories with no long term studies make me uneasy as well. Well it is a stretch. The covid19 vaccines have passed all known testing metrics for safety. Keep in mind that passing is not a perfect score. But the same measures were applied to these vaccines that have been applied to all other vaccines. So in this measure they are essentially the same. What is different is how the covid19 vaccines were derived. This is where the ‘express lane’ was taken that is new. And what’s ‘new’ is not the end goal but the route taken. So to make the Ebola vaccine they knew what they needed and took the traditional long route albeit as fast as they could. We could’ve done the same for covid19 and we’d have the same results in another 12 to 18 months and nowhere near enough vaccine to make much difference at that juncture. Basically they used a man made biological catalyst to speed up the processes to get to the same place they’d have gone otherwise. So it is not as dire as perhaps it sounds and it is working and it is more efficacious than any influenza vaccine ever produced. I’d suggest that we should swell up with pride at the accomplishment and relish what the effort may bring us in the very near future in the form of other drugs. 2 Link to comment Share on other sites More sharing options...
tube fanatic Posted January 28, 2021 Share Posted January 28, 2021 Brazilian mutation found in Minnesota. Scientists very concerned about this one: https://www.npr.org/sections/goatsandsoda/2021/01/27/961108577/why-scientists-are-very-worried-about-the-variant-from-brazil Maynard Link to comment Share on other sites More sharing options...
OO1 Posted January 28, 2021 Share Posted January 28, 2021 How the Coronavirus Turns the Body Against Itself Some patients struggling with Covid-19 develop antibodies against their own tissues, scientists have found. https://www.nytimes.com/2021/01/28/health/coronavirus-antibodies-immunity.html https://www.deccanherald.com/science-and-environment/how-the-coronavirus-turns-the-body-against-itself-944495.html Link to comment Share on other sites More sharing options...
OO1 Posted January 28, 2021 Share Posted January 28, 2021 A Troubling New Pattern Among the Coronavirus Variants The most concerning versions of the virus are not simply mutating—they’re mutating in similar ways. https://www.theatlantic.com/health/archive/2021/01/coronavirus-evolving-same-mutations-around-world/617721/ Link to comment Share on other sites More sharing options...
OO1 Posted January 28, 2021 Share Posted January 28, 2021 On 1/27/2021 at 12:06 PM, billybob said: Moderna is developing a booster for the S African variant, just in case. Anecdotal but info online. Moderna are really looking like they are best solution overall ------or at least they try the hardest 1 Link to comment Share on other sites More sharing options...
billybob Posted January 28, 2021 Share Posted January 28, 2021 5 minutes ago, RandyH000 said: Moderna are really looking like they are best solution overall ------or at least they try the hardest Phizers is developing a booster also. That Brazil variant am sure the are aware of. Link to comment Share on other sites More sharing options...
Bosco-d-gama Posted January 28, 2021 Share Posted January 28, 2021 Ruh - Roh............. Looks like Cuomo could be in for a code brown, a well deserved code brown.😔 https://www.foxnews.com/politics/new-york-nursing-home-report-reveals-massive-corruption-coverup-scandal Link to comment Share on other sites More sharing options...
oldtimer Posted January 28, 2021 Share Posted January 28, 2021 Here's a link with a little more detail: N.Y. Severely Undercounted Virus Deaths in Nursing Homes, Report Says (msn.com) Kind of underscores the cognitive dissonance in those who have steadily maintained the death tolls have been exaggerated. Link to comment Share on other sites More sharing options...
CECAA850 Posted January 28, 2021 Author Share Posted January 28, 2021 23 minutes ago, oldtimer said: Here's a link with a little more detail: N.Y. Severely Undercounted Virus Deaths in Nursing Homes, Report Says (msn.com) Kind of underscores the cognitive dissonance in those who have steadily maintained the death tolls have been exaggerated. Motives of the two groups are completely different. Cuomo needs to go go. Link to comment Share on other sites More sharing options...
oldtimer Posted January 28, 2021 Share Posted January 28, 2021 1 minute ago, CECAA850 said: Motives of the two groups are completely different. Cuomo needs to go go. No dog in that hunt for me. I don't live there, and am proud to say have no relatives there. 1 Link to comment Share on other sites More sharing options...
CECAA850 Posted January 28, 2021 Author Share Posted January 28, 2021 6 minutes ago, oldtimer said: No dog in that hunt for me. I don't live there, and am proud to say have no relatives there. I grew up in New York and still have family there. I don't recognize it anymore. Link to comment Share on other sites More sharing options...
richieb Posted January 28, 2021 Share Posted January 28, 2021 Cuomo’s constant finger pointing proves the adage - point your finger to others and three are pointed back at you. I’m sure his brother can spin this to their advantage - Link to comment Share on other sites More sharing options...
oldtimer Posted January 28, 2021 Share Posted January 28, 2021 1 Link to comment Share on other sites More sharing options...
Moderators Travis In Austin Posted January 28, 2021 Moderators Share Posted January 28, 2021 2 hours ago, RandyH000 said: Moderna are really looking like they are best solution overall ------or at least they try the hardest Got my 2nd Moderna Injection last night, with our son. Still alive. 2 Link to comment Share on other sites More sharing options...
oldtimer Posted January 28, 2021 Share Posted January 28, 2021 4 minutes ago, dwilawyer said: Got my 2nd Moderna Injection last night, with our son. Still alive. What group were you classified and why? Link to comment Share on other sites More sharing options...
OO1 Posted January 28, 2021 Share Posted January 28, 2021 1 hour ago, dwilawyer said: Got my 2nd Moderna Injection last night, with our son. Godspeed Link to comment Share on other sites More sharing options...
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