Without knowing more about your amp and setup, for now, my answer is no to using a KT 66 in place of a 6v6 that the amp may have been designed for. The KT 66 is a stronger power tubes, pin configuration may not work, and the bias requirements between the two tubes, 8v8 and KT 66 are significantly different.
Damaged amp, damaged tube and poor performance is a likely reward. The SQ is not based on tube size or power. An El 84 can sound as good as a 300b in the right setting. The key is to build a system that fits you and not end up with a bunch of gear and excess tubes sitting around.